Predicting the long-termoutcome of patients admitted with acute heart failure to the emergency department using renal markers

Abstract Introduction Renal dysfunction is one of the most important comorbidities in patients with chronic heart failure (HF) and frequently accentuated setting acute HF (AHF). Serum creatinine blood urea nitrogen (BUN) have been classically used as markers renal dysfunction, despite having several limitations. High (BUN)/creatinine ratio has associated higher mortality HF. We aimed to predict long-term outcome admitted emergency department using markers. Methods 900 our diagnosed AHF were retrospectively analysed. Patients divided into 4 groups according BUN SCr on admission: – ≤33 mg/dL ≤1.56 (group LowBUN/LowCr), n=544; >1.56 mg/dl LowBUN/HighCr), n=25; >33 HighBUN/LowCr), n=131; HighBUN/HighCr), n=200; The primary end-point this study was occurrence all-cause during follow-up. Results median (IQR) level admission 28.0 (20) mg/dL, 1.15 (0.73) mg/d, mean age 81±7 years, 50.8% (n=457) women follow up 7 months. A total 41.2% diabetic, 21.7% had at least mild COPD, CAD present 28.9% cases, 44.0% valvular disease 68.4% atrial fibrillation. Creatinine, Cr/BUN predicted survival 6 months (p<0.05). Survival lowest group HighBUN/HighCr highest LowBUN/LowCr. As expected, BUN/Cr HighBUN/LowCr LowBUN/HighCr. Conclusions Despite not ratio, showed worst prognosis. Funding Acknowledgement Type funding sources: None.